BACKGROUND: Mega-dose sodium ascorbate (NaAscorbate) appears beneficial in experimental sepsis. ...Vasopressor dose and SOFA score changes over time showed faster reductions with NaAscorbate (P < 0.001 and P = 0.042). The sodium level, however, increased m
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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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1934 | 12 |
1935 | 18 |
1936 | 20 |
1937 | 17 |
1938 | 19 |
1939 | 9 |
1940 | 10 |
1941 | 19 |
1942 | 12 |
1943 | 15 |
1944 | 12 |
1945 | 107 |
1946 | 185 |
1947 | 197 |
1948 | 166 |
1949 | 145 |
1950 | 264 |
1951 | 338 |
1952 | 311 |
1953 | 285 |
1954 | 312 |
1955 | 252 |
1956 | 232 |
1957 | 249 |
1958 | 236 |
1959 | 217 |
1960 | 240 |
1961 | 298 |
1962 | 280 |
1963 | 431 |
1964 | 560 |
1965 | 481 |
1966 | 468 |
1967 | 506 |
1968 | 553 |
1969 | 619 |
1970 | 620 |
1971 | 636 |
1972 | 563 |
1973 | 636 |
1974 | 639 |
1975 | 682 |
1976 | 541 |
1977 | 528 |
1978 | 484 |
1979 | 533 |
1980 | 564 |
1981 | 543 |
1982 | 604 |
1983 | 607 |
1984 | 611 |
1985 | 654 |
1986 | 610 |
1987 | 606 |
1988 | 562 |
1989 | 627 |
1990 | 663 |
1991 | 702 |
1992 | 754 |
1993 | 729 |
1994 | 842 |
1995 | 844 |
1996 | 828 |
1997 | 907 |
1998 | 963 |
1999 | 950 |
2000 | 1138 |
2001 | 1174 |
2002 | 1193 |
2003 | 1322 |
2004 | 1319 |
2005 | 1452 |
2006 | 1444 |
2007 | 1546 |
2008 | 1582 |
2009 | 1588 |
2010 | 1682 |
2011 | 1835 |
2012 | 1923 |
2013 | 2043 |
2014 | 1984 |
2015 | 1972 |
2016 | 1897 |
2017 | 1900 |
2018 | 2038 |
2019 | 2248 |
2020 | 2394 |
2021 | 2367 |
2022 | 2481 |
2023 | 2449 |
2024 | 930 |
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Tests of subinhibitory concentrations of sodium ascorbate on cell signals were performed using a reporter strain assay. Sub-MICs of sodium ascorbate resulted in significant reduction of the signalling molecules C4-HSL and 3-oxo-C12-HSL (P < 0.01). .
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